German Stem Cell Engineering:
The Science of a Better You

Numerous types of stem cell therapies are available at ANOVA. Stem cell research brought insights that allowed for technological advancements in therapies and expanding the knowledge of the underlying mechanisms of stem cells. This has allowed for more effective therapies to be developed.

Bone Marrow Concentrate (BMC) is one of the most commonly applied source of stem cells. Despite the fact that the actual number of stem cells in BMC is biologically limited, several other (regenerative) factors in BMC have been shown to deliver promising results in the treatment of numerous diseases.

Stem Cell Therapies 2.0: The ANOVA Stem Cell Secretome Therapy is the next generation of stem cell-based therapies. It was designed to harness and mass produce the healing essences of stem cells (paracrine and regenerative factors, extracellular vesicles, exosomes) in a uniquely designed laboratory process.

Fat (adipose) derived Mesenchymal Stem Cells (MSC | adMSCs) are a commonly used source of stem cells, because of their availability and robustness. They communicate to other cells with a broad spectrum of secreted paracrine and regenerative factors. They are our favorite source of stem cells for the production of the secretome.

Platelet Rich Plasma (PRP) is a blood-derived, cellular product with concentrated supply of regenerative growth factors and cytokines. Its efficacy has been proven in some orthopedic conditions. When used in combination with our stem cell therapies, its efficacy is synergistically enhanced.

Rejuvenation therapy is a form of medical treatment with the focus to halt, alter and even reverse the aging process. While there is currently no scientifically proven way to delay our internal aging processes themselves, there are ways to alter or delay some of the effects we experience as we age. Stem cell therapy is on the rise as a rejuvenation treatment. In this article, we discuss the differences between the various stem cell therapies for anti-aging.

Parkinson's Disease (PD) is one of the most common diseases of the nervous system. There is currently no cure for the disease. Common treatments aim at easing symptoms and reducing side effects as much as possible. A big part of the therapy usually includes medication. But are there other options? Can alternative treatments enhance the effect of typical PD therapies, or even stop the progression of the disease? Here we provide an overview of treatment options for PD.

Amyotrophic lateral sclerosis (ALS) is a very serious disease of the central and peripheral nervous system. With the exception of the rare hereditary forms, its cause is still unknown. Even though they are often compared, ALS has nothing to do with MS (Multiple Sclerosis) - they are two completely different diseases.
About one to two out of 100,000 people develop ALS each year. The disease usually begins between the ages of 50 and 70; younger adults are rarely affected. Men are affected slightly more often than women (1.6:1). The frequency of ALS appears to be increasing worldwide. Disease progress varies greatly from patient to patient, and life expectancy is significantly shortened.
Currently, there is no known cure for ALS, but stem cell-based therapies may give patients, their doctors and scientists hope in dealing with this condition.

The term “exosomes” has frequently been in the news in recent years. They have been known to biologists since their discovery in the 1980s, but they remain something unknown to most other people. As their relevance in the pharmaceutical and medical field increases, we want to explain in simple ways what exosomes are, and why they are disrupting science.

Degenerative disc disease (DDD) is one of the most common sources of back pain and affects approximately 30 million people every year. It can lead to a chronic debilitating condition and can have a serious negative impact on a person's quality of life. Although several structures within the spine have been identified as sources of pain, the intervertebral disc accounts for approx. 40-50% of all chronic lower back pain. When pain from DDD is severe, traditional non-operative treatment may be ineffective.
Recent research has shown that the injection of bone marrow stem cells into degenerating discs can halt and in some cases even reverse their degeneration. This is important, because this in turn slows down or halts the cascade of secondary problems resulting from a degenerating discs, such as chronic back pain, restricted motion, spinal cord and nerve root compression with radiating pain in arms and legs, deformation and inflammation in vertebral bodies (osteochondrosis), facet joint arthrosis and others.