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Mit diesen Stammzell-Produkten führen wir unsere Behandlungen durch

Stem Cell Therapies Treatments sorted by stem cell type (source tissue) and product

News & Insights

ANOVA’s Stem Cell Secretome (SCS) Therapy in three steps

Step 1 - Harvesting Mesenchymal Stem Cells (MSCs) from subcutaneous adipose tissue.

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At Anova IRM, we use the most advanced harvesting technique to date, the so-called "nutational infrasonic liposuction", employing the Euromi Lipomatic® system. This procedure provides 10 to 100 times more viable MSCs obtained from the harvested adipose tissue than any other technique.

In a point-of-care setting, like at Anova, the adipose tissue is immediately processed according to current highest standards, guaranteeing the highest quality of the end product.

Step 2 - Processing the Stem Cells and designing the Stem Cell Secretome (SCS)

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In our specialized laboratories, the “stromal vascular fraction” (SVF) is isolated from adipose tissue after enzymatic digestion. The SVF is a mixture of different types of cells. It contains a high percentage of MSCs (equivalent of up to 500.000 cells per gram), and is one of the highest amounts of MSCs to be found in the human body.

By subjecting the cells to external stimuli, they can be stimulated to secrete a high concentration of cytokines, micro-RNAs and growth factors (that retain regenerative abilities) that are packed in extracellular vesicles (microvesicles and exosomes). Together, these factors make up the secretome.

In the next step the cells are laboratory grown and expanded, where the MSCs are obtained by special technique. These MSCs can now be used for the mass production of the Mesenchymal Stem Cell Secretome (MSEC). MSEC consists of a high concentration of the extremely effective healing substances that are secreted by the MSCs.

The stem cell secretome is ready for use, and can be stored for several months at minus 80°C. This makes it possible to design a therapy plan that allows for several infusions (over several years) and favors optimal treatment outcomes possible.

Step 3 - Application and treatment with Anova’s Stem Cell Secretome therapy

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From a single isolation of stem cells, from the liposuction of the adipose tissue, up to 10 therapeutic doses can be obtained that are to be administered systemically via an infusion. The first application of SSEC is possible 3 days after liposuction, while the earliest application of MSEC is possible 21 days after liposuction. During that time, our specialists in the laboratory prepare and concentrate the product. In parallel, several pharmaceutical level quality tests are conducted to verify that the product is safe and of the highest quality standards, that we are aiming for.

News & Insights

News & Insights